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Rheumatology — diagnosis and treatment | MCQs

Rheumatology — diagnosis and treatment | MCQs

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Question 1 of 5

1. Question

What does canakinumab act on?

TNFa
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?IL-1ß
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T cells
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IL-6
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Question 2 of 5

2. Question

The following steps are recommended for people with osteoarthritis. Tick all that apply

Increasing physical activity, stopping smoking, reducing alcohol intake (=2 units/day), and adequate calcium and vitamin D intake.
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Decreasing physical activity, stopping smoking, reducing alcohol intake (=2 units/day), and adequate calcium and vitamin D intake.
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Weight loss, thermo-therapy, transcutaneous electrical nerve stimulation, assistive devices (walking sticks and tap turners), manual therapy (manipulation and stretching).
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Weight loss, thermotherapy, transcutaneous electrical nerve stimulation, decrease
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Question 3 of 5

3. Question

What is the mechanism of action behind denosumab?

Denosumab stimulates bone formation by osteoblasts by binding to the receptor activator of nuclear factor-?ß (RANKL).
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Denosumab inhibits bone resorption by binding to the receptor activator of nuclear factor-?ß (RANKL).
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Denosumab stimulates bone formation by osteoblasts through inhibition of IL-1ß.
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Denosumab inhibits bone resorption through inhibition of IL-1ß.
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Question 4 of 5

4. Question

According to NICE guidelines, this is the first-line treatment for rheumatoid arthritis:

Methotrexate and low-dose glucocorticoids until the DMARD takes effect.
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Leflunomide and low-dose glucocorticoids until the DMARD takes effect.
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Salazopyrin and low-dose glucocorticoids until the DMARD takes effect.
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Any of the above.
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Question 5 of 5

5. Question

Which of the following statements are true? Tick all that apply

The term ‘arthritis’ is often used to refer to any disorder that affects the joints, whereas rheumatic diseases usually affect joints, tendons, ligaments, bones, and muscles.
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The goal of therapy in rheumatic and musculoskeletal disorders is reversal of the disease process.
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Most people with hypermobile joints do not have any issues.
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People with fibromyalgia may also have decreased sensitivity to pain.
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